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Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice
Kinetic studies of mold alpha-galactosidase on PNPG hydrolysis
is a macrolide antibiotic used to treat bovine respiratory disease (BRD) in cattle and swine respiratory disease in pigs
CCC1=CC=C(CC2=CC=C3CO[C@]4(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C3=C2)C=C1
Chemical Name: 5-fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide
Wedelolactone 2098 Novel small-molecule PGC-1α transcriptional regulatorWedelolactone, a natural product from Ecliptae herba, suppresses LPS induced caspase 11 expression by directly inhibiting the IKK Complex[1]. Wedelolactone inhibits 5 lipoxygenase (5 Lox) (IC50~2. 5 M) activity by an oxygen radical scavenging mechanism. Wedelolactone induces caspase dependent apoptosis in prostate cancer cells via downregulation of PKC without inhibiting Akt[2]. Anti cancer, anti inflammatory, and antioxidant activities. Product
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