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PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group
SCH442416 (0
Administration of 2-PMPA (50mg/kg) produces a mean peak concentration of 2-PMPA of 29
Smiles: COC1=CC=C(C=C1OC1CCCC1)[C@H]1CC(=O)NC1
Garcia-Cabezas MA
Elesclomol AY-600 PROTAC FKBP Degrader-3 is aElesclomol, also known as STA 4783, is a HSP 90 Inhibitor, and is a small molecule bis(thio hydrazide amide) with oxidative stress induction, pro apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative
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