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6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle
1 μM in direct measurement of pyruvate transport into rat liver and yeast mitochondria
It is a good chemical tool to enable interrogation of GPR39 signaling in different cellular contexts
20)21)23-17(24-16)22-14-5-3-2-4-6-14
Smiles: CC1=CC2C=C(C=CC=2N1)OC1C=CN=C(NC2=CC(CS(=O)(=O)NCCN(C)C)=CC=C2)N=1
Dovitinib-D8 zine-d3 6-dione is a naturally occurringDovitinib D8 (CHIR 258 D8) is the deuterium labeled Dovitinib. Dovitinib (CHIR 258) is a multi targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8 9, 10 13 8, 27 210 nM for FLT3, c Kit, FGFR1 FGFR3, VEGFR1 VEGFR2 VEGFR3 and PDGFR PDGFR, respectively. Product information CAS Number: 1246819 84 0 Molecular Weight: 400. 48 Formula: C21H21FN6O Chemical Name: 4 amino 5 fluoro 3 {6 [4 methyl(2,2,3,3,5,5,6,6 H)piperazin 1 yl] 1H 1,3 benzodiazol 2 yl}