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NH125 inhibits eEF-2 kinase activity (IC50 = 60 nM) in vitro
85-34-96)42(59(75)103)15-17-52(72)97)62(106)82-31-55(100)88-50(28-54(74)99)67(111)90-45(16-18-53(73)98)63(107)92-48(26-39-29-81-43-13-10-9-12-41(39)43)64(108)86-38(7)61(105)94-58(37(5)6)69(113)83-32-56(101)87-49(27-40-30-79-33-84-40)66(110)91-47(25-36(3)4)65(109)89-44(60(76)104)20-23-114-8/h9-10
although it may also be used to treat asthma or irritable bowel syndrome
Acoramidis (AG10) stimulates the mitochondrial QO2 in a concentration-dependent manner between 10 and 100 μM
Smiles: CC1=NC=C(Cl)C=C1NCC1=CC=C(S1)C(=O)N[C@@H](CC1CCCC1)C(=O)NC1CC1
3-Methylcarbazole N-452 NH125 inhibits eEF-2 kinase activity3 Methylcarbazole is an carbazole alkaloid compound with anticancer effects. 3 Methylcarbazole shows growth inhibitory activity (IC50 of 25 g mL) on human fibrosarcoma HT 1080 cells. Product information CAS Number: 4630 20 0 Molecular Weight: 181. 23 Formula: C13H11N Chemical Name: 3 methyl 9H carbazole Smiles: CC1C=C2C(=CC=1)NC1=CC=CC=C21 InChiKey: PHKYYUQQYARDIU UHFFFAOYSA N InChi: InChI=1S C13H11N c1 9 6 7 13 11(8 9)10 4 2 3 5 12(10)14 13 h2