Novobiocin Sodium toside) 18 ± 6nM for PC3

18 ± 6nM for PC3 cells

1'-biphenyl]-3-ol

including Ki67

39)/t21-/m0/s1

and identified the IC50 for PARP-1 inhibition to be around 6 nM and the total ablation of PARP-1 activity to be at concentrations of 30−100 nM

Novobiocin Sodium toside) 18 ± 6nM for PC3Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. Product information CAS Number: 1476 53 5 Molecular Weight: 634. 61 Formula: C31H35N2NaO11 Synonym: Albamycin Cathomycin Chemical Name: (3R,4S,5R,6R) 5 hydroxy 6 ({4 hydroxy 3 [4 hydroxy 3 (3 methylbut 2 en 1 yl)benzamido] 8 methyl 2 oxo 2H