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InChi: InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18
JC124 also significantly reduces protein expression levels of NLRP3
It down-regulates CDK4 and cyclin D1 expression while does not effect other CDKs and cyclins
Smiles: CC(C)=CCOC1C=CC(=CC=1)C1=C(CC(C)C)C(=O)OC1=O
and neuroprotection of hippocampal neurons against cell death caused by systemic administration of the excitotoxin kainate
AZ-PFKFB3-67 quarterhydrate acarb InChi: InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18AZ PFKFB3 67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively. Product information Molecular Weight: 460. 01 Formula: C104H102N20O13 Chemical Name: (2S) N [4 [3 cyano 1 [(3, 5 dimethyl 1, 2 oxazol 4 yl)methyl]indol 5 yl]oxyphenyl]pyrrolidine 2 carboxamide quarterhydrate Smiles: O. CC1=NOC(C)=C1CN1C=C(C#N)C2=CC(=CC=C12)OC1C=CC(=CC=1)NC(=O)[C@@H]1CCCN1.
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