TyK2-IN-2 aminomethyl and has strong anti-cancer activity

and has strong anti-cancer activity

Smiles: CN([C@H](CN1CC[C@H](O)C1)C1C=CC=CC=1)C(=O)C(C1C=CC=CC=1)C1C=CC=CC=1

The gepotidacin MIC90s are as follows (in μg/mL): Streptococcus pyogenes

Smiles: CCCCC1C(=O)N(C2CCCCC2)C(=O)NC1=O

Smiles: NC1N=CN=C2C=1C(=CN2C1CCCC1)C1C=CC(=CC=1)OC1C=CC=CC=1

TyK2-IN-2 aminomethyl and has strong anti-cancer activityTyK2 IN 2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0. 1 M and 0. 05 M for TYK2 JH2, IL 23 and IFN, respectively. TyK2 IN 2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2 IN 2 can be used for the research of inflammatory and autoimmune diseases. Product information CAS Number: 2098466 94 3 Molecular Weight: 310. 35 Formula: C16H18N6O Chemical Name: 6 [(3,5 dimethylphenyl)amino] 8