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selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2
Formula: C11H11FN2O2
Formula: C19H24NO3
but side effects were problematic and it is unclear whether cilomalast will be marketed
and it can be produced in starved androgen-responsive prostate cancer cells
T025 Catalog No.:M28407-C selectively inhibits JAK2 mediated phosphorylationT025 is an orally available and highly potent Cdc2 like kinase (CLK) inhibitor with Kds of 4. 8, 0. 096, 6. 5, and 0. 61 nM for CLK1, CLK2, CLK3, and CLK4, respectively. Product information CAS Number: 2407433 00 3 Molecular Weight: 382. 42 Formula: C21H18N8 Chemical Name: N2 methyl N4 [(pyrimidin 2 yl)methyl] 5 (quinolin 6 yl) 7H pyrrolo[2,3 d]pyrimidine 2,4 diamine Smiles: CNC1N=C(NCC2N=CC=CN=2)C2=C(NC=C2C2C=CC3=NC=CC=C3C=2)N=1 InChiKey:
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