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Naratriptan icorandil 4-dichlorophenyl)methyl]amino]-adenosine

SKU: 11220411833

4.6
USD85.00 USD116.00

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Description

4-dichlorophenyl)methyl]amino]-adenosine

2-dicarboxamide

InChi: InChI=1S/C25H34N6O3/c1-17(2)22-16-34-25(33)31(22)23-9-10-26-24(28-23)27-18(3)21-7-5-20(6-8-21)15-29-11-13-30(14-12-29)19(4)32/h5-10

6(2):651-61

Smiles: N[C@@H](CC1C=CC=CC=1)C(=O)N1C/C(=C\C2=CC(Cl)=C(Cl)C=C2)/C(=O)/C(/C1)=C/C1=CC(Cl)=C(Cl)C=C1

Naratriptan icorandil 4-dichlorophenyl)methyl]amino]-adenosineNaratriptan is a selective 5 HT1 receptor subtype agonist for the treatment of migraine headache. Naratriptan binds with high affinity to human cloned 5 HT1B 1D receptors. Migraines are likely due to local cranial vasodilatation and or to the release of sensory neuropeptides (including substance P and calcitonin gene related peptide) through nerve endings in the trigeminal system. The therapeutic activity of AMERGE for the treatment of migraine

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