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Formula: C19H21N5O
CN(CC(O)COC1C=CC(=CC=1)NS(C)(=O)=O)CCC1C=CC(Cl)=C(Cl)C=1
the most effective dose
InChi: InChI=1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3
3)4/h5-21H2
Caspase-3/7 Inhibitor I Catalog No.:M23015-C Formula: C19H21N5OCaspase 3 7 inbibitor I is a potent, reversible, isatin sulfonamide based inhibitor of caspase 3 (KI(app) = 60 nM) and caspase 7 (KI(app) = 170 nM). Is a weaker inhibitor of caspase 9 (Ki(app) = 3. 1 mM). It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase 1, caspase 2, caspase 4, caspase 6, and caspase 8. It has been shown to inhibit apoptosis in camptothecin treated Jurkat cells (IC50 ~50 M). Also it has been reported to
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