c-Kit-IN-3 Size:Contact [email protected] for quotation IC50≈8 nM)

IC50≈8 nM)

1) GNF-6231 shows IC50s of greater than 10 μM on all CYP isoforms tested2) GNF-6231 have favorable potency and a PK profile across preclinical species upon oral administration

endometriosis

Oxytetracycline is an important member of the bacterial aromatic polyketide family

HM-JF526 NHS

c-Kit-IN-3 Size:Contact [email protected] for quotation IC50≈8 nM)c Kit IN 3 (Compound 18) is a potent and selective c KIT kinase inhibitor with an IC50 of 4 nM. c Kit IN 3 displays great potencies against c KIT kinase and a broad spectrum of drug resistant mutants in the biochemical assay. c Kit IN 3 has improved bioavailability. c Kit IN 3 (Compound 18; 0. 1 10 M; 6 days; primary GIST patient cells) exhibits dose dependent antiproliferative effects. c Kit IN 3 (Compound 18; 0. 01 1 M; 24 hours; GIST T1, GIST T1