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and by Fyrlklövern Scandinavia as triButyrate
PubMed PMID: 25515519
3(11):e428]
The IC50s for Dp44mT growth inhibition are 48±9 nM and 60±12 nM
Similarly in the proliferation assay
Lometrexol hydrate - CAS# 1435784-14-7 Size:2mg solid and by Fyrlklövern Scandinavia asLometrexol hydrate (DDATHF hydrate), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine
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