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RRx-001 7464 AT-7519 free base is a

SKU: 20142523968

4.6
USD100.00 USD138.00

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Description

AT-7519 free base is a drug that acts as a multi-cyclin-dependent kinase inhibitor for Cdk1/cyclin B

2 μM and 20 μM reduces IL-1beta secretion by LPS-activated mixed glia cultures after 1 and 3 days of exposure

InChiKey: HCFDWZZGGLSKEP-NPMXJOAUSA-N

InChi: InChI=1S/C13H13BrN2OS/c1-10-3-4-12(11(14)9-10)17-7-8-18-13-15-5-2-6-16-13/h2-6

2-Methylthio-AMP (2-MeSAMP) inhibits agonist-mediated αIIbβ3 activation in platelets

RRx-001 7464 AT-7519 free base is aRRx 001, a hypoxia selective epigenetic agent and studied as a radio and chem sensitizer, triggers apoptosis and overcomes drug resistance in myeloma. RRx 001 exhibits potent anti tumor activity with minimal toxicity. RRx 001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP . RRx 001 is a potent inhibitor of G6PD and shows potent antimalarial activity. Product information CAS Number: 925206 65 1 Molecular Weight: 268. 02

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