NAV-2729 19862 Smiles: CC(NC1C(=CN=C2C=CC(=CC=12)C1=CN=C(COC)C=C1)C(N)=O)C1CCOCC1

Smiles: CC(NC1C(=CN=C2C=CC(=CC=12)C1=CN=C(COC)C=C1)C(N)=O)C1CCOCC1

52 ng/mL and an AUC of 532

6 nM and 253 nM for TYK2

MG-277 potently inhibits tumor cell growth in a p53-independent manner

ALS-008112 enters various types of epithelial cells in the respiratory tract and is subsequently phosphorylated to form an intracellular nucleoside triphosphate with a half-life of approximately 29 hours

NAV-2729 19862 Smiles: CC(NC1C(=CN=C2C=CC(=CC=12)C1=CN=C(COC)C=C1)C(N)=O)C1CCOCC1NAV 2729 is a dual Arf1 Arf6 activation inhibitor. Product information CAS Number: 419547 11 8 Molecular Weight: 456. 88 Formula: C25H17ClN4O3 Chemical Name: 2 benzyl 3 (4 chlorophenyl) 5 (4 nitrophenyl) 1H,7H pyrazolo[1,5 a]pyrimidin 7 one Smiles: [O ][N+](=O)C1C=CC(=CC=1)C1=CC(=O)N2NC(CC3C=CC=CC=3)=C(C2=N1)C1C=CC(Cl)=CC=1 InChiKey: WHYGBVWGARJOCS UHFFFAOYSA N InChi: InChI=1S C25H17ClN4O3 c26 19 10 6 18(7 11 19)24 22(14 16 4 2 1 3 5 16)28 29 23(31)15