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α2-adrenoceptors mediate many physiological actions of endogenous noradrenaline and catecholamines adrenaline
CAS Number: 145265-02-7
AZD-8529 mesylate does not elicit antagonist responses on mGluRs at 25 μM
Angiotensin II causes hypertension by activating AT1 receptors in the kidney promoting sodium reabsorption
to phoma stem canker disease caused by Leptosphaeria maculans
AL 8810 isopropyl ester pyl α2-adrenoceptors mediate many physiological actionsEC50: 430 nM AL 8810 is a a FP receptor antagonist. Prostaglandin F receptor (FP), a receptor belonging to the prostaglandin (PG) group of receptors, binds to and mediates the biological actions of Prostaglandin F2 (PGF2). In vitro: Previous study found that AL 8810 had weak agonist potency in A7r5 cells and 3T3 fibroblasts. AL 8810 exhibited properties of an apparent competitive antagonist, which was demonstrated by producing parallel dextral shifts
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