D-I03 Size:Contact [email protected] for quotation 54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21

54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21

001) tumor volume reductions

and suppresses production of pro-inflammatory cytokines

Macrophage migration inhibitory factor promotes proliferation and neuronal differentiation of neural stem/precursor cells through Wnt/β-catenin signal pathway

thereby preventing tumor cell replication

D-I03 Size:Contact [email protected] for quotation 54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21D I03 is a selective RAD52 inhibitor with a Kd of 25. 8 M. D I03 specifically inhibits RAD52 dependent single strand annealing (SSA) and D loop formation with IC50s of 5 M and 8 M, respectively. D I03 suppresses growth of BRCA1 and BRCA2 deficient cells and inhibits formation of damage induced RAD52 foci, but does not effect on RAD51 foci induced by Cisplatin. Product information CAS Number: 688342 78 1 Molecular Weight: 428. 64 Formula: C23H36N6S