Bis-(N, N'-PEG4-NHS ester)-Cy5 lirioferine Veledimex can cross blood-brain barrier

Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys

Smiles: CC1C=C(CN)C=C(C)C=1NC(=O)C1=CC=C(O1)C1=CC(Cl)=CC=C1Cl

7% in the old MAs when compared with 85 ± 5% in the old salt arteries (P<0

InChiKey: QEHVTUCLCBXQIC-UHFFFAOYSA-N

CAS Number: 382-45-6

Bis-(N, N'-PEG4-NHS ester)-Cy5 lirioferine Veledimex can cross blood-brain barrierBis (N,N' PEG4 NHS ester) Cy5 is an alkyl ether based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2107273 48 1 Molecular Weight: 1081. 64 Formula: C55H73ClN4O16 Chemical Name: 1 {15 [(2,5 dioxopyrrolidin 1 yl)oxy] 15 oxo 3,6,9,12 tetraoxapentadecan 1 yl} 2 [5 (1 {15 [(2,5 dioxopyrrolidin 1 yl)oxy] 15 oxo 3,6,9,12 tetraoxapentadecan 1 yl} 3,3 dimethyl 2,3 dihydro 1H indol 2 ylidene)penta 1,3 dien 1 yl]