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It blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells
PubMed PMID: 23421678
Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent
but shows no effect on NF-κB
The (Z)-isomer has been consigned the name BMS-205912
M-110 0192 It blocks LPS-induced expression ofM 110 is a inhibitor of protein arginine N methyltransferases (PRMTs). It is also a highly isoform selective, cell permeable and potent ATP competitive inhibitor of the PIM kinase family that prefers PIM 3, shown to inhibit the proliferation of prostate cancer cell lines with IC50s between 0. 6 to 0. 9 M, with no activity on normal human peripheral blood mononuclear cells up to 40 M. Product information CAS Number: 1395048 49 3 Molecular Weight: 445.
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