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SB-743921 HCl Catalog No.:M7949-2 700874-72-2

SKU: 4124062907

4.8
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Description

700874-72-2

3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide

3 μM) but not p110α/p85α PI3K (IC50>100 μM)

which is structurally an analogue of naproxen

PF-4800567 has little effect on the circadian clock at 32 nM

SB-743921 HCl Catalog No.:M7949-2 700874-72-2SB 743921 is a synthetic small molecule with potential antineoplastic properties. SB 743921 selectively inhibits kinesin spindle protein (KSP), an important protein involved in the early stages of mitosis that is expressed in proliferating cells. Inhibition of KSP results in inhibition of mitotic spindle assembly and interrupts cell division, thereby causing cell cycle arrest and induction of apoptosis. Product information CAS Number: 940929 33 9

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