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Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression
LDN-212854 exhibits some selectivity for ALK2 in preference to other BMP type I receptors
Multiple Myeloma (2009)
Smiles: COC1=CC(=CC=C1NC1=NC(=C(Cl)C=N1)C1=CNC2=CC=CC=C21)N1CCC(N)CC1
PF-06952229 (oral gavage
VU-1545 yl-Hesperidin Enhancer of Zeste Homolog 2VU 1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM) with a Ki of 156 nM and an EC50 of 9. 6 nM. Product information CAS Number: 890764 63 3 Molecular Weight: 402. 38 Formula: C22H15FN4O3 Chemical Name: N [1 (2 fluorophenyl) 3 phenyl 1H pyrazol 5 yl] 4 nitrobenzamide Smiles: [O ][N+](=O)C1C=CC(=CC=1)C(=O)NC1=CC(=NN1C1=CC=CC=C1F)C1C=CC=CC=1 InChiKey: BRAZLURTFMCAHU UHFFFAOYSA N InChi: InChI=1S C22H15FN4O3 c23 18 8 4
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