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YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells
promote VEGF induced HUVEC cell migration
CAS Number: 457961-34-1
Molecular Weight: 439
(241):77-83
Enzastaurin - CAS# 170364-57-5 0280 YM-90709 inhibits the binding ofEnzastaurin, CAS No. 170364 57 5, also known as DB 102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) stimulated neo angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Product information CAS Number: