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Suppression of Plk1 in vivo by using GSK461364 results in mitotic arrest with aberrant mitotic figures consisting of monopolar or collapsed mitotic spindles
it lowers intraocular pressure by reducing aqueous humor secretion
JK184 was dosed orally 0
1997 Apr 25
LQZ-7I has improved cytotoxicity with IC50s of 3
(3R,4S)-Tofacitinib - CAS# 1092578-46-5 lexin Hydrochloride Suppression of Plk1 in vivoTofacitinib, also known as tasocitinib, CP 690550, is a Janus kinase (JAK) inhibitor. Product information CAS Number: 1092578 46 5 Molecular Weight: 312. 37 Formula: C16H20N6O Chemical Name: 3 [(3R,4S) 4 methyl 3 [methyl({7H pyrrolo[2,3 d]pyrimidin 4 yl})amino]piperidin 1 yl] 3 oxopropanenitrile Smiles: CN([C@H]1CN(CC[C@@H]1C)C(=O)CC#N)C1N=CN=C2NC=CC2=1 InChiKey: UJLAWZDWDVHWOW AAEUAGOBSA N InChi: InChI=1S C16H20N6O c1 11 5 8 22(14(23)3 6 17)9
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