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Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease
37-/m0/s1/i1D3
InChi: InChI=1S/C19H21N3O3S/c1-22(2)26(24
but Octreotide alone does not in PCK rats
InChiKey: OZPZCETZTBBQBO-UHFFFAOYSA-N
PF-04859989 hydrochloride Catalog No.:M30145-C Sphingomyelin metabolism is associated withPF 04859989 hydrochloride is a brain penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC50s of 23 and 263 nM for hKAT II and rKAT II. PF 04859989 hydrochloride is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 M, respectively). Product information CAS Number: 177943 33 8 Molecular Weight: 214. 65 Formula: C9H11ClN2O2 Chemical Name: (3S) 3 amino 1 hydroxy 1,2,3,4 tetrahydroquinolin 2 one
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