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N-piperidine Ibrutinib hydrochloride Catalog No.:M30823-C Koyanagi et al

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Description

Koyanagi et al

4 μM for rat small intestine NK-2 receptor

5% was equally efficacious as Vancomycin (VAN) in a methicillin-resistant S

InChi: InChI=1S/C16H21NO2/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17(13)19/h7-8

The herb of lotus leaves is a commonly used traditional Chinese medicine with a wide range of pharmacological and physiological activities

N-piperidine Ibrutinib hydrochloride Catalog No.:M30823-C Koyanagi et alN piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51. 0 and 30. 7 nM for WT BTK and C481S BTK, respectively. N piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY 133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7. 9 nM. Product information CAS Number:

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