RuBi-Glutamate e Y (human) 5-dihydro-1H-imidazol-2-yl)hydrazin-1-ylidene]methyl]anthracen-9-yl}methylidene)hydrazin-1-yl]-4

5-dihydro-1H-imidazol-2-yl)hydrazin-1-ylidene]methyl]anthracen-9-yl}methylidene)hydrazin-1-yl]-4

Dihexa has a long circulating half-life

shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ

Treatment of MM cell lines with EZM 2302 leads to inhibition of PABP1 and SMB methylation and cell stasis with IC50 values in the nanomolar range (9

InChi: InChI=1S/C16H19N3O5S

RuBi-Glutamate e Y (human) 5-dihydro-1H-imidazol-2-yl)hydrazin-1-ylidene]methyl]anthracen-9-yl}methylidene)hydrazin-1-yl]-4Product information CAS Number: 1220121 59 4 Molecular Weight: 970. 54 Formula: C28H32F12N5Na2O4P3Ru Chemical Name: ruthenium(2+) disodium bis(2,2' bipyridine) bis(hexafluoro phosphanuide) trimethylphosphane 2 aminopentanedioate Smiles: [Na+].[Na+].[Ru+2]. CP(C)C. NC(CCC([O ])=O)C([O ])=O. F[P ](F)(F)(F)(F)F. F[P ](F)(F)(F)(F)F. C1C=CC=NC=1C1=CC=CC=N1. C1C=CC=NC=1C1=CC=CC=N1 InChiKey: SQQVSHWHIPVYSZ UHFFFAOYSA L InChi: InChI=1S 2C10H8N2. C5H9NO4.