c-met-IN-1 60233 Tazemetostat hydrobromide inhibits the activity

Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 with a Ki value of 2

Andrzej Wróbel

Smiles: C[C@@H](O)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](N)CC1C=CC=CC=1)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O

Solubility: DMSO : 105 mg/mL (324

Note: Tapentadol HCl is discontinued | Tapentadol is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI)

c-met-IN-1 60233 Tazemetostat hydrobromide inhibits the activityc met IN 1 (compound 16) is a potent and selective c Met inhibitor, with IC50 of 1. 1 nM, with antitumor activity.. Product information CAS Number: 2084836 84 8 Molecular Weight: 640. 70 Formula: C35H37FN6O5 Chemical Name: N [3 fluoro 4 ({6 methoxy 7 [3 (4 methylpiperazin 1 yl)propoxy]quinolin 4 yl}oxy)phenyl] 1 (2 methoxyphenyl) 1H imidazole 4 carboxamide Smiles: CN1CCN(CCCOC2=CC3=NC=CC(OC4=CC=C(C=C4F)NC(=O)C4=CN(C=N4)C4=CC=CC=C4OC)=C3C=C2OC)CC1