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NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2
Chemical Name: 5-(2-carboxyethyl)-6-{[(5E)-6-(4-methoxyphenyl)hex-5-en-1-yl]oxy}-9-oxo-9H-xanthene-2-carboxylic acid
Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs
but causes no change in other CCCs
Review of the pharmacology
Acid-PEG9-NHS ester Size:Contact [email protected] for quotation NS-3-008 hydrochloride is an orallyAcid PEG9 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1895916 27 4 Molecular Weight: 611. 63 Formula: C26H45NO15 Chemical Name: 31 [(2,5 dioxopyrrolidin 1 yl)oxy] 31 oxo 4,7,10,13,16,19,22,25,28 nonaoxahentriacontanoic acid Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O InChiKey: BJOKQEMLFQBOQZ UHFFFAOYSA N InChi: InChI=1S C26H45NO15 c28 23 1 2 24(29)27(23)42