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Genz-123346 and a few other GCS inhibitors are substrates for multi-drug resistance efflux pumps such as P-gp (ABCB1
one of a series of second-generation
Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%
The MIC value for M
selective and cell-permeable p300 histone acetyltransferase (HAT) inhibitor with IC50 of 5 μM
Orlistat Size:Solid 10 mg Genz-123346 and a few otherOrlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider supervised reduced calorie diet. Product information CAS Number: 96829 58 2 Molecular Weight: 495. 73 Formula: C29H53NO5 Chemical Name: (2S) 1 [(2S,3S) 3 hexyl 4 oxooxetan 2 yl]tridecan 2 yl (2S) 2
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