Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 9 - Aug 14
antineoplastic and anti-fibrotic activities
InChiKey: PTTQXDBPTFOCMT-UHFFFAOYSA-N
InChiKey: AQXXZDYPVDOQEE-MXDQRGINSA-N
and metabolic stability in human and mouse liver microsomes
SAR131675 is the first highly specific VEGFR-3-TK inhibitor described to date
BGB-283 ide Rb3 antineoplastic and anti-fibrotic activitiesBGB 283 is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. BGB 283 potently inhibits BRafV600E activated ERK phosphorylation and cell proliferation. It demonstrates selective cytotoxicity and preferentially inhibits proliferation of cancer cells harboring BRafV600E and EGFR mutation amplification. In BRafV600E colorectal cancer cell lines, BGB 283 effectively inhibits
US$ 625.00
US$ 750.00
US$ 600.00
US$ 1000.00
US$ 625.00
US$ 1200.00
US$ 1250.00
US$ 1200.00
US$ 1250.00
US$ 400.00
US$ 1250.00
US$ 1000.00
US$ 500.00
US$ 750.00
US$ 600.00
US$ 1200.00