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R-(+)-ETOMOXIR - CAS# 124083-20-1 093 Epub 2016 Jan 6

SKU: 89248473796

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Description

Epub 2016 Jan 6

Chemical Name: Neuronal-LSB3i

Molecular Weight: 591

300586-90-7

Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a)

R-(+)-ETOMOXIR - CAS# 124083-20-1 093 Epub 2016 Jan 6R (+) ETOMOXIR, CAS No. 124083 20 1, is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as

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