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4-Methylhistamine dihydrochloride Catalog No.:M22257-C InChi: InChI=1S/C40H50N8O6

SKU: 75417976857

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Description

InChi: InChI=1S/C40H50N8O6

InChiKey: OGXMGJGFLBSEJW-HNNXBMFYSA-N

FC1C=CC(=CC=1)C(C1C=CC(F)=CC=1)N1CCN(C/C=C/C2C=CC=CC=2)CC1

30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37

4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H

4-Methylhistamine dihydrochloride Catalog No.:M22257-C InChi: InChI=1S/C40H50N8O64 Methylhistamine dihydrochloride (or 4 methylhistamine) is a selective agonist of H4 receptor with a pEC50 value of 7. 40. 1 (=1) . In the chemotaxis of mast cells and leukocytes to sites of inflammation, the histamine H4 receptor (H4R) is involved . In transfected cells, 4 methylhistamine bound to hH4R with the highest affinity, compared to the binding to other histamine receptors. The interaction between 4 methylhistamine and hH4R showed a higher

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