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JNJ28871063 hydrochloride - CAS# 944342-90-9 Size:Contact [email protected] for quotation 4-triol is an endogenous metabolite

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Description

4-triol is an endogenous metabolite

Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCOCCC(=O)OC(C)(C)C

TTA-A2 can be used for the research of a variety of human neurological diseases

an ingredient from Aconitum carmichaelii Debx

InChiKey: MECDPCCFIDQBBP-UHFFFAOYSA-N

JNJ28871063 hydrochloride - CAS# 944342-90-9 Size:Contact [email protected] for quotation 4-triol is an endogenous metaboliteJNJ28871063 hydrochloride is an orally active, highly selective and ATP competitive pan ErbB kinase inhibitor with IC50 values of 22 nM, 38 nM, and 21 nM for ErbB1, ErbB2, and ErbB4, respectively. JNJ28871063 hydrochloride inhibits phosphorylation of functionally important tyrosine residues in both EGFR and ErbB2. JNJ28871063 hydrochloride crosses the blood brain barrier and has antitumor activity in human tumor xenograft models that overexpress EGFR

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