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InChi: InChI=1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33
CAS Number: 501919-59-1
Smiles: COC1C=CC=C(OC)C=1C1C=CC(C[C@H](NC(=O)C2C(Cl)=CC=CC=2Cl)C(O)=O)=CC=1
CAS Number: 1883518-31-7
2(6):1492-7
FD-IN-1 eceptor antagonists-2 InChi: InChI=1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33FD IN 1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD IN 1 also inhibits factor XIa (FXIa) and Tryptase 2 with IC50s of 7. 7 and 6. 5 M, respectively. Product information CAS Number: 1646682 14 5 Molecular Weight: 377. 43 Formula: C23H23NO4 Chemical Name:
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