Loxapine succinate - CAS# 27833-64-3 oxy)-1 6-dihydroxy-2-methyl-9 10-anthracenedione J Spinal Cord Med

J Spinal Cord Med

June 14¨C17

Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia

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Loxapine succinate - CAS# 27833-64-3 oxy)-1 6-dihydroxy-2-methyl-9 10-anthracenedione J Spinal Cord MedLoxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti psychotic agent. IC50 value: Target: D2DR D4DR; 5 HT receptor in vitro: In the presence of Loxapine, [3H]ketanserin binds to 5 HT2 receptor in Frontal cortex of brain in human and bovine with ki value of 6. 2 nM and 6. 6 nM, respectively. Loxapine has the rank order of potency for the various receptors appears to be as follows: 5