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DBM 1285 dihydrochloride 311727 cerebrospinal fluid and brain tissue

SKU: 84824794477

4.2
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Description

cerebrospinal fluid and brain tissue

000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites

(Rac)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) used for the research of cognition/memory disorders

326 nM and EC50s of 2850

) decreases brain pH and suppresses electrographic post-asphyxia seizures in rats

DBM 1285 dihydrochloride 311727 cerebrospinal fluid and brain tissueProduct information Molecular Weight: 468. 42 Formula: C21H24Cl2FN5S Chemical Name: N cyclopropyl 4 [4 (4 fluorophenyl) 2 (piperidin 4 yl) 1,3 thiazol 5 yl]pyrimidin 2 amine dihydrochloride Smiles: Cl. Cl. FC1C=CC(=CC=1)C1N=C(SC=1C1C=CN=C(NC2CC2)N=1)C1CCNCC1 InChiKey: ANQWETXPBPZVOF UHFFFAOYSA N InChi: InChI=1S C21H22FN5S. 2ClH c22 15 3 1 13(2 4 15)18 19(28 20(27 18)14 7 10 23 11 8 14)17 9 12 24 21(26 17)25 16 5 6 16;; h1 4,9,12,14,16,23H,5 8,10

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