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Doxorubicin Hydrochloride - CAS# 25316-40-9 Catalog No.:M10308-2 every other day) impairs mammary

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Description

every other day) impairs mammary tumor growth in syngeneic orthotopic E0771-C57BL/6 mouse model

PubMed Central PMCID: PMC3383737

InChi: InChI=1S/C21H22ClN3O2/c1-4-18-19(22)20(25(3)24-18)21(26)23-13-15-7-11-17(12-8-15)27-16-9-5-14(2)6-10-16/h5-12H

Smiles: CN([C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C1=NC=CS1)OC)[C@@H](C)CC)C(=O)[C@@H](NC(=O)C(C)(C)N)C(C)C

10(11):1859-67

Doxorubicin Hydrochloride - CAS# 25316-40-9 Catalog No.:M10308-2 every other day) impairs mammaryDoxorubicin free base, also called doxorubicin, is an anthracycline antibiotic with antineoplastic activity. Approved API for cancer therapeutic use is doxorubicin HCl. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Note: Doxorubicin

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