Clenbuterol (hydrochloride) necionine Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3

Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology

InChiKey: PDKDOPJQPKXNCT-UHFFFAOYSA-N

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CNC2=O

Picroside-I

Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

Clenbuterol (hydrochloride) necionine Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3Clenbuterol is a sympathomimetic 2 adrenoceptor agonist. 2 adrenoceptor agonists, mainly long acting 2 adrenoceptor agonists, are an important pharmacological approach to induce bronchodilation in patients with chronic obstructive pulmonary disease. In vitro: A hormone dependent human breast cancer cell line was treated with different concentrations of clenbuterol. It was found that clenbuterol could stimulate cell proliferation at low concentrations,